A METHOD FOR THE REGULATION OF PROTEIN KINASE ACTIVITY IN VIVO AND IN VITRO

摘要

Disclosed herein is a substantially pure nucleic acid encoding a eukaryotic protein kinase having at least one mutated amino-acid residue located in its subdomain IX. Also disclosed is a substantially pure eukaryotic protein kinase polypeptide having at least one mutation in its subdomain IX, the kinase being encoded by the nucleic acid.