发明名称 |
MATERIAL AND METHOD FOR ALTERING IMMUNE RESPONSE TO EXOGENOUS AND ENDOGENOUS IMMUNOGEN, INCLUDING SYNGENEIC AND NON-SYNGENEIC CELL, TISSUE OR ORGAN |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a tissue engineering solution for achieving immunomodulation without reliance on chemicals or pharmaceuticals which compromise a patient's immune system. <P>SOLUTION: The invention provides an implantable material for reducing an immune response or an inflammatory reaction, comprising a biocompatible matrix, and, anchored or embedded endothelial cells, endothelial-like cells, or analogs thereof, wherein the implantable material is provided to a recipient in an amount sufficient to reduce the immune response or inflammatory reaction in the recipient. <P>COPYRIGHT: (C)2013,JPO&INPIT |
申请公布号 |
JP2012224644(A) |
申请公布日期 |
2012.11.15 |
申请号 |
JP20120181692 |
申请日期 |
2012.08.20 |
申请人 |
MASSACHUSETTS INST OF TECHNOLOGY <MIT>;PERVASIS THERAPEUTICS INC |
发明人 |
EDELMAN ELAZER R;NUGENT HELEN MARIE;METHE HEIKO |
分类号 |
A61K35/36;A61P29/00;A61P37/06;C12N5/071 |
主分类号 |
A61K35/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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