发明名称 RADIOLABELLING
摘要 Compounds of the formula (I) are disclosed: 18F—(CHR)n(CH2)mCHO  (I) in which n and m are independently 0 and 1 with at least one of n and m being 1, and R (if present) is a hydrogen atom or a methyl group, subject to the proviso that if n is 1 and R is methyl then m is 0. Synthesis of the compounds is described together with their use in radiolabelling reactions, e.g. for the radiolabelling of peptides to facilitate detection by Positron Emission Tomography (PET) imaging. The preferred compound is [18F]Fluoroacetaldehyde.
申请公布号 US2012288445(A1) 申请公布日期 2012.11.15
申请号 US201213447030 申请日期 2012.04.13
申请人 PRENANT CHRISTIAN;THE UNIVERSITY OF MANCHESTER 发明人 PRENANT CHRISTIAN
分类号 C07C47/14;A61K51/04;C07C45/27;C07H21/00;C07K1/13;C07K2/00;C07K14/00;C07K16/00 主分类号 C07C47/14
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