发明名称 LIPID MEMBRANE STRUCTURE CAPABLE OF IMIGRATING TO TARGET CELL AND METHOD FOR PRODUCING SAME, AND METHOD FOR SCREENING FOR SUBSTANCE EXHIBITING EFFECT THEREOF IN TARGET CELL
摘要 <p>[Problem] To provide: a lipid membrane structure capable of migrating to a target cell; an agent for preventing/treating obesity, an agent for preventing/treating adipose tissue inflammations, and an agent for preventing/treating the accumulation of fat in a non-adipose tissue, each of which comprises the lipid membrane structure; a method for producing the lipid membrane structure; a method for screening for a substance exhibiting an effect thereof in a target cell, which utilizes the lipid membrane structure; and a method for screening for an agent for preventing/treating obesity, an agent for preventing/treating adipose tissue inflammations or an agent for preventing/treating the accumulation of fat in a non-adipose tissue. [Solution] A lipid membrane structure capable of migrating to a target cell, and comprising a lipid membrane as a sole membrane, wherein the lipid membrane comprises, as constituent lipids, a lipid comprising a peptide capable of migrating to a target cell, a long-chain PEG and a lipid bound together in this order and a lipid having a short-chain PEG bound thereto.</p>
申请公布号 WO2012153616(A1) 申请公布日期 2012.11.15
申请号 WO2012JP60622 申请日期 2012.04.19
申请人 NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;HARASHIMA HIDEYOSHI;KAJIMOTO KAZUAKI;AKITA HIDETAKA;HYODO MAMORU;MD. NAZIR HOSSEN 发明人 HARASHIMA HIDEYOSHI;KAJIMOTO KAZUAKI;AKITA HIDETAKA;HYODO MAMORU;MD. NAZIR HOSSEN
分类号 A61K9/127;A61K9/10;A61K38/00;A61K38/16;A61K45/00;A61K47/24;A61K47/34;A61K47/42;A61P3/04;A61P43/00;C07K7/06;C12Q1/02 主分类号 A61K9/127
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