发明名称 |
Amorphous drug transdermal systems, manufacturing methods, and stabilization |
摘要 |
The present invention refers to a transdermal delivery device comprising a backing layer, an adhesive matrix layer comprising a supersaturated concentration of an active agent substantially in amorphous form within the adhesive matrix, and a release liner. The present invention also refers to a method of preparing an adhesive matrix containing at least one supersaturated active agent substantially in amorphous form. Further, the present invention refers to a method to stabilize and a method to reestablish the meta-stable amorphous-drug transdermal system during its manufacturing, storing, shipping and handling process. |
申请公布号 |
EP2522339(A2) |
申请公布日期 |
2012.11.14 |
申请号 |
EP20120179591 |
申请日期 |
2008.03.11 |
申请人 |
MYLAN TECHNOLOGIES, INC. |
发明人 |
TANG, JIANSHENG;DEVERICH, JOSEPH, M.;MILLER, KENNETH, J., II.;BESTE, RUSSELL, D. |
分类号 |
A61K9/70 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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