发明名称 |
Layered non-fouling, antimicrobial antithrombogenic coatings |
摘要 |
Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material. |
申请公布号 |
US8308699(B2) |
申请公布日期 |
2012.11.13 |
申请号 |
US20090632669 |
申请日期 |
2009.12.07 |
申请人 |
ZHANG ZHENG;HUVAL CHAD;O'SHAUGHNESSEY WILLIAM SHANNAN;HENCKE MICHAEL;SQUIER TREVOR;LI JUN;BOUCHARD MICHAEL;LOOSE CHRISTOPHER R.;SEMPRUS BIOSCIENCES CORP. |
发明人 |
ZHANG ZHENG;HUVAL CHAD;O'SHAUGHNESSEY WILLIAM SHANNAN;HENCKE MICHAEL;SQUIER TREVOR;LI JUN;BOUCHARD MICHAEL;LOOSE CHRISTOPHER R. |
分类号 |
A61M25/00;C08F20/56;C08F112/08;C08F120/10;C08F283/02;C08F283/04;C08F290/14;C08G77/38 |
主分类号 |
A61M25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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