Microorganism producing O-acetyl-homoserine and the method of producing O-Acetyl-homoserine using the microorganism

摘要

Disclosed herein are a microorganism strain capable of producing the L-methionine precursor O-acetyl homoserine in high yield and a method of producing O-acetyl homoserine using the same. The microorganism strain is a strain of Escherichia sp. in which an acetyl-CoA synthase gene ( acs ) and/or a pantothenate kinase gene ( coaA ) encoding a pantothenate kinase gene refractory to feedback inhibition by CoA is introduced and expressed.