发明名称 |
Heterocyclic compounds for the inhibition of integrins and use thereof |
摘要 |
The present invention relates to compounds of formula (I) wherein: A is a radical selected from the group comprising aromatic heterocyclic 5-membered ring systems; Ar is a radical selected from the group comprising optionally substituted 5- and 6-membered aromatic ring systems, whereby the ring system contains 0, 1, 2 or 3 heteroatoms selected from the group comprising N, O and S; Z is a linker and Ψ is a radical of formula (II) and their use for the inhibition of integrin. |
申请公布号 |
US8309735(B2) |
申请公布日期 |
2012.11.13 |
申请号 |
US20070300530 |
申请日期 |
2007.05.14 |
申请人 |
ZISCHINSKY GUNTHER;STRAGIES ROLAND;OSTERKAMP FRANK;SCHARN DIRK;HUMMEL GERD;KALKHOF HOLGER;ZAHN GRIT;VOSSMEYER DOERTE;CHRISTNER-ALBRECHT CLAUDIA;REINEKE ULRICH;SHIRE ORPHAN THERAPIES GMBH |
发明人 |
ZISCHINSKY GUNTHER;STRAGIES ROLAND;OSTERKAMP FRANK;SCHARN DIRK;HUMMEL GERD;KALKHOF HOLGER;ZAHN GRIT;VOSSMEYER DOERTE;CHRISTNER-ALBRECHT CLAUDIA;REINEKE ULRICH |
分类号 |
C07D213/72;A61K31/44 |
主分类号 |
C07D213/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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