发明名称 |
Process for producing laurolactam |
摘要 |
Provided is a process for efficiently producing laurolactam by simple steps from cyclododecanone and hydroxylamine. This production process comprises the steps of: (a) reacting cyclododecanone with hydroxylamine in an aqueous solution in the presence of an oxime-formation solvent to produce cyclododecanone oxime; (b) separating the reaction mixture obtained after the oxime-forming step into an oil and an aqueous phases and collecting a solution of cyclododecanone oxime of the oil phase; (c) removing a part or all of the oxime-formation solvent and dissolved water from the solution of cyclododecanone oxime which is collected as an oil phase in the oil/aqueous phase separation step, whereby preparing a solution containing a rearrangement solvent to be used in a rearrangement reaction in a later step and the cyclododecanone oxime; (d) producing laurolactam from cyclododecanone oxime by rearrangement reaction using an aromatic-ring containing compound as a rearrangement catalyst; and (e) separating and removing the rearrangement solvent and the rearrangement catalyst from the reaction mixture after the rearrangement step, and purifying the laurolactam. |
申请公布号 |
US8309714(B2) |
申请公布日期 |
2012.11.13 |
申请号 |
US20080744675 |
申请日期 |
2008.11.19 |
申请人 |
KUGIMOTO JUNICHI;KAWAI JOJI;SHIMOMURA HIDEO;YASUMATSU RYOUTA;II NOBUHIRO;UBE INDUSTRIES, LTD. |
发明人 |
KUGIMOTO JUNICHI;KAWAI JOJI;SHIMOMURA HIDEO;YASUMATSU RYOUTA;II NOBUHIRO |
分类号 |
C07D201/04;C07D225/02 |
主分类号 |
C07D201/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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