发明名称 Detoxifying methods for extracts of Corydalis Tuber and Pharbitidis seed, detoxified herbal extracts manufactured by the same, and compositions for preventing and treating a gastrointestinal dyskinetic disease comprising the herbal extracts
摘要 PURPOSE: A composition containing crude drug extract is provided to be used as a therapeutic agent for treating gastrointestinal disorders. CONSTITUTION: A method for preparing Corydalis Tuber, Pharbitis seed extract or a mixture thereof with reduced toxicity comprises a step of mixing Corydalis Tuber, Pharbitis seed, or a mixture thereof using water, low alcohol of C1-4, or a mixture solvent thereof at 10-15 Deg. C. for24-72 hours. The solvent is 30-70% ethanol solution. A pharmaceutical composition further contains ingredient with an effect of treating gastrointestinal movement disorder. The pharmaceutical composition further contains domperidone, metoclopramide, levosulpiride, mosapride, itopride, erythromycin, and cisapride. [Reference numerals] (AA) Corydalis Tuber and Pharbitis mixture 120g (100g+20g); (BB) Adding 1200ml of 50% ethanol; (CC) Stirring and extracting at 10°C~15°C, for 24~72 hours; (DD) Filtering; (EE) Residue; (FF) Corydalis Tuber and Pharbitis mixture extract; (GG) Concentrating by reduced pressure; (HH) 40°C~50°C; (II) Corydalis Tuber and Pharbitis mixture soft extract(6g)
申请公布号 KR101199946(B1) 申请公布日期 2012.11.12
申请号 KR20120076053 申请日期 2012.07.12
申请人 发明人
分类号 A61K36/505;A61K36/736;A61P1/00;A61P1/04 主分类号 A61K36/505
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