摘要 |
Described is a diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy, comprising exposing primary tumor cells from a patient, e.g., tumor cells obtained from a brain tumor or pancreatic cancer, to (i) a parvovirus and/or (ii) a chemotherapeutic agent or radiotherapy, and determining the reduction of the expression or concentration of ISG15. |
申请人 |
UNIVERSITATSKLINIKUM HEIDELBERG;DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTES;RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG |
发明人 |
GIESE, NATHALIA;WERNER, JENS;BUCHLER, MARKUS;GIESE, THOMAS;DAFFLER, LAURENT;CZIEPLUCH, CELINA;ROMMELAERE, JEAN;RAYKOV, ZAHARI |