AN ANTIBODY SPECIFICALLY BINDING TO INSULIN-LIKE GROWTH FACTOR-1
摘要
The present invention relates to an isolated antibody that specifically binds to an epitope comprised in the stretch of amino acids ranging from amino acid 76 to amino acid 84 as known for human insulin-like growth factor-1 precursor (SEQ ID NO:1). The novel antibodies are of great utility since they allow for the sensitive and specific detection of insulin-like growth factor-1 even in the presence of high excess concentration of the closely related insulin-like growth factor-2. Detection of insulin-like growth factor-1 is e.g. possible in a bodily fluid sample.
申请公布号
CA2831162(A1)
申请公布日期
2012.11.08
申请号
CA20122831162
申请日期
2012.05.04
申请人
F. HOFFMANN-LA ROCHE AG
发明人
ANDRES, HERBERT;DUEFEL, HARTMUT;GERG, MICHAEL;KOWALEWSKY, FRANK;SCHOLZ, CHRISTIAN;SCHRAEML, MICHAEL