发明名称 |
Methods for Decreasing Ocular Toxicity of Antibody Drug Conjugates |
摘要 |
The invention relates to charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of using the same to reduce ocular toxicity associated with administration of antibody drug conjugates.
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申请公布号 |
US2012282282(A1) |
申请公布日期 |
2012.11.08 |
申请号 |
US201213439493 |
申请日期 |
2012.04.04 |
申请人 |
LUTZ ROBERT J.;CHARI RAVI V.J.;IMMUNOGEN, INC. |
发明人 |
LUTZ ROBERT J.;CHARI RAVI V.J. |
分类号 |
A61K39/395;A61P35/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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