发明名称 |
SYNTHETIC PEPTIDE CAPABLE OF INDUCING EXPRESSION OF TYPE-2 TNF RECEPTOR AND USE THEREOF |
摘要 |
Provided are: a composition for inducing the expression of TNFR2, which contains a peptide having a high activity of inducing the expression of TNFR2 as an active ingredient; and a method for producing a cell that expresses TNFR2 in a selective manner, which utilizes the composition. The method for producing the cell provided according to the present invention comprises: a step of culturing a cell capable of expressing at least one type-2 TNF receptor; and a step of supplying a synthetic peptide comprising a nuclear localization signal sequence (NLS) or a nucleolus localization signal sequence (NoLS) to the cell to increase the expression amount of the type-2 TNF receptor in the cell. |
申请公布号 |
WO2012150676(A1) |
申请公布日期 |
2012.11.08 |
申请号 |
WO2012JP60369 |
申请日期 |
2012.04.17 |
申请人 |
TOAGOSEI CO.,LTD.;KOBAYASHI NAHOKO;YOSHIDA TETSUHIKO;NIWA MIKIO |
发明人 |
KOBAYASHI NAHOKO;YOSHIDA TETSUHIKO;NIWA MIKIO |
分类号 |
C12N5/10;A61K38/00;A61P5/50;A61P9/00;A61P25/28;A61P43/00;C07K14/47 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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