发明名称 |
METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF GENETIC AND RETINAL DISEASE |
摘要 |
A process of detecting the presence of or susceptibility to a disease involving the Frizzled-4 receptor is provided. The inventive method determines the presence or absence of one or more mutations in Frizzled-4 alone or in conjunction with other proteins such as Norrin and LRP5. The presence of a mutation predicts the presence of a disease or susceptibility to a disease. The inventive process further provides correction or prevention of a disease by administration of frizzled-4 to a subject to alter or maintain a physiological function. |
申请公布号 |
US2012282230(A1) |
申请公布日期 |
2012.11.08 |
申请号 |
US201013503444 |
申请日期 |
2010.10.20 |
申请人 |
DRENSER KIMBERLY |
发明人 |
DRENSER KIMBERLY |
分类号 |
A61K48/00;A61K35/12;A61K38/17;A61P9/10;A61P15/08;A61P27/02;A61P35/00;C12Q1/68 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|