发明名称 |
Method for increasing permeability of an epithelial barrier |
摘要 |
Disclosed are nanotopography-based methods and devices for interacting with a component of epithelial tissue and increasing the permeability of the tissue. Devices include structures fabricated on a surface to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. Microneedles may be beneficially utilized for delivery of an agent to a cell or tissue. Devices may be utilized to directly or indirectly alter cell behavior through the interaction of a fabricated nanotopography with the components of epithelial tissue. |
申请公布号 |
AU2011311255(A1) |
申请公布日期 |
2012.11.08 |
申请号 |
AU20110311255 |
申请日期 |
2011.04.27 |
申请人 |
KIMBERLY-CLARK WORLDWIDE, INC. |
发明人 |
ROSS, RUSSELL FREDERICK |
分类号 |
A61M37/00;A61M5/158 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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