METHODS AND HELPER VIRUSES FOR THE GENERATION OF RNA VIRUS
摘要
The present invention provides a method for generating negative-stranded segmented RNA viruses using linear expression constructs in the presence of helper virus which comprises at least one amino acid modification within the N-terminal cytoplasmic region of the NA protein.
申请公布号
WO2011151470(A3)
申请公布日期
2012.11.08
申请号
WO2011EP59284
申请日期
2011.06.06
申请人
AVIR GREEN HILLS BIOTECHNOLOGY RESEARCH DEVELOPMENT TRADE AG;MUSTER, THOMAS;EGOROV, ANDREJ;WOLSCHEK, MARKUS