| 发明名称 |
RNAI MODULATION OF APOB AND USES THEREOF |
| 摘要 |
<p>The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.</p> |
| 申请公布号 |
EP1802644(B1) |
申请公布日期 |
2012.11.07 |
| 申请号 |
EP20050802154 |
申请日期 |
2005.09.26 |
| 申请人 |
ALNYLAM PHARMACEUTICALS INC. |
发明人 |
SOUTSCHEK, JUERGEN;VORNLOCHER, HANS-PETER;HADWIGER, PHILIPP;ELBASHIR, SAYDA |
| 分类号 |
C12N15/113;A61K31/70;C07H21/04;C12N5/00 |
主分类号 |
C12N15/113 |
| 代理机构 |
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| 主权项 |
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| 地址 |
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