发明名称 |
POLYPEPTIDE HETERODIMERS AND USES THEREOF |
摘要 |
<p>This disclosure provides immunoglobulin binding molecules that specifically bind to human macrophage stimulating receptor (MST1 R, also referred to herein as recepteur d'origine Nantaise or RON), including antibodies and monospecific and multispecific single chain binding proteins having one or more other domains, such as one or more antibody constant region domains. Also provided are therapeutic applications of such binding proteins, such as for the treatment of cancer and inflammatory disorders.</p> |
申请公布号 |
EP2519544(A1) |
申请公布日期 |
2012.11.07 |
申请号 |
EP20100805670 |
申请日期 |
2010.12.29 |
申请人 |
EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC |
发明人 |
BLANKENSHIP, JOHN, W.;TAN, PHILIP |
分类号 |
C07K16/46;A61K39/395;A61P35/00;A61P37/00 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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