Water soluble anti cancer agent with Heparin-DTX conjugates and preparing method for the same

摘要

PURPOSE: A water soluble anticancer agent and a method for manufacturing the same are provided to overcome low water solubility. CONSTITUTION: A method for preparing a water soluble anticancer agent comprises: a step of removing sodium salt from low molecular weight heparin; a step of introducing amine groups to docetaxel; a step of mixing the heparin and docetaxel; and a step of purifying the self-aggregated heparin-docetaxel assembly. The molar ratio of the heparin and docetaxel is 1:1-10.