发明名称 |
KINETIC RESOLUTION |
摘要 |
Whilst methodologies for the Kinetic Resolution of alcohols are well established, no analogous direct methods exist for the highly selective, direct catalytic Kinetic Resolution of thiols (i.e., R—SH). The present invention relates to a method for resolving stereoisomeric mixtures of thiols. In particular, the present invention relates to purely organocatalytic mediated resolution of enantiomeric mixtures of thiols without the need for enzymes. Also disclosed are some novel catalysts. Such catalysts may comprise a cinchona alkaloid-derived moiety. |
申请公布号 |
US2012277437(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
US201013515092 |
申请日期 |
2010.12.07 |
申请人 |
CONNON STEPHEN JOSEPH;PESCHIULLI ALDO;PROCURANTI BARBARA;THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY |
发明人 |
CONNON STEPHEN JOSEPH;PESCHIULLI ALDO;PROCURANTI BARBARA |
分类号 |
C07C327/22;C07C51/083;C07D453/04 |
主分类号 |
C07C327/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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