发明名称 |
METHODS FOR MODULATING BACTERIAL INFECTION |
摘要 |
The present invention relates to methods for treating or reducing the risk of or preventing diseases caused by or associated with pathogenic bacteria. More particularly, the present invention relates to methods for treating or reducing the risk of or preventing diseases caused by or associated with pathogenic bacteria of the gastrointestinal (GI) tract. The present invention further relates to methods for promoting pathways induced by commensal bacteria of the GI tract that lead to Th17 differentiation, which in turn leads to localized and systemic accumulation of Th17 cells. Compositions and medicaments are also described herein that are used alleviate and/or prevent symptoms associated with diseases caused by or associated with pathogenic bacteria. Accordingly, the compositions, medicaments and methods described herein may be used to address the needs of patients or subjects that would benefit from increased Th17 cell differentiation. |
申请公布号 |
US2012276149(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
US201013501615 |
申请日期 |
2010.10.15 |
申请人 |
LITTMAN DAN;IVANOV IVAYLO;BRODIE EOIN;UMESAKI YOSHINORI;HONDA KENYA |
发明人 |
LITTMAN DAN;IVANOV IVAYLO;BRODIE EOIN;UMESAKI YOSHINORI;HONDA KENYA |
分类号 |
A61K35/74;A61K38/17;A61P31/04;A61P37/04 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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