发明名称 |
COMBINATION OF A PHOSPHATIDYLINOSITOL-3-KINASE (PI3K) INHIBITOR AND A MTOR INHIBITOR |
摘要 |
The present invention relates to a pharmaceutical combination comprising a phosphatidylinositol- 3-kinase (PI3K) inhibitor compound which is a 2-carboxamide cycloamino urea derivative or a pharmaceutically acceptable salt thereof and at least one mammalian target of rapamycin (mTOR) inhibitor or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising such a combination; and the uses of such a combination in the treatment proliferative diseases, more specifically of mammalian target of rapamycin (mTOR) kinase dependent diseases. |
申请公布号 |
CA2833962(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
CA20122833962 |
申请日期 |
2012.04.23 |
申请人 |
NOVARTIS AG |
发明人 |
FRITSCH, CHRISTINE;GARCIA-ECHEVERRIA, CARLOS;HUANG, XIZHONG;MAIRA, SAUVEUR-MICHEL |
分类号 |
A61K31/436;A61K31/4439;A61P35/00 |
主分类号 |
A61K31/436 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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