发明名称 |
TOLEROGENIC SYNTHETIC NANOCARRIERS FOR GENERATING CD8+ REGULATORY T CELLS |
摘要 |
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.
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申请公布号 |
US2012276155(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
US201213457936 |
申请日期 |
2012.04.27 |
申请人 |
KISHIMOTO TAKASHI KEI;FRASER CHRISTOPHER;MALDONADO ROBERTO A.;SELECTA BIOSCIENCES, INC. |
发明人 |
KISHIMOTO TAKASHI KEI;FRASER CHRISTOPHER;MALDONADO ROBERTO A. |
分类号 |
A61K39/00;A61K9/00;A61P29/00;A61P37/06;A61P41/00;B82Y5/00;C12N5/0783;G01N33/577 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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