发明名称 NOVEL 3-HYDROXYISOTHIAZOLE 1-OXIDE DERIVATIVE
摘要 [Object] To provide a GPR40 activating agent containing, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the compound or the salt, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases. [Means of Solving the Problem] A compound of Formula (I): (where p is 0 to 4; j is 0 to 2; k is 0 to 1; a ring A is an aryl group, a heterocyclic group, a cycroalkyl group, a cycroalkenyl group, a spirocyclic group; a ring B is an aryl group, a heteroaryl group; X is 0 or —NR7—; and R1 to R7 and L are specific groups), a salt of the compound, or a solvate of the compound or the salt.
申请公布号 US2012277150(A1) 申请公布日期 2012.11.01
申请号 US201213444595 申请日期 2012.04.11
申请人 OHKOUCHI MUNETAKA;MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 OHKOUCHI MUNETAKA
分类号 A61K31/427;A61K31/425;A61K31/438;A61K31/4439;A61K31/4709;A61K31/496;A61K31/4985;A61K31/506;A61K31/513;A61K31/522;A61K31/5377;A61K38/26;A61K38/28;A61P3/10;A61P39/06;C07D275/03;C07D417/12;C07D417/14;C07D471/10;C07D491/107;C07D491/20 主分类号 A61K31/427
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