发明名称 |
TREATMENT OF SEX HORMONE BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SHBG |
摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sex Hormone Binding Globulin (SHBG), in particular, by targeting natural antisense polynucleotides of Sex Hormone Binding Globulin (SHBG). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SHBG.
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申请公布号 |
US2012277290(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
US201113520503 |
申请日期 |
2011.01.11 |
申请人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;CURNA, INC. |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA |
分类号 |
A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61P3/00;A61P3/10;A61P15/08;A61P25/00;A61P25/18;A61P25/22;A61P25/30;C07H21/04;C12N5/071;G01N25/04 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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