摘要 |
[Problem] To provide a GPR40 activating agent having as an active ingredient a novel compound having a GPR40 agonist action, or a salt thereof, a solvate of the compound or salt, or the like; in particular, an insulin secretagogue or an agent for preventing and/or treating diabetes, obesity, or the like. [Solution] A compound represented by formula (III) [Chemical formula 1] (in the formula, f is 0-2; g is 1-4; j is 0-3; k is 0-2; n is 0-2; p is 0-4; h is 0-3; q1 is 0-3; q2 is 0 or 1; r1 is 0-2 (where q1+q2+r1 is 0-5); J1a is -CR11a- or a nitrogen atom; J2 is -CR12aR12b- or -NR12c-; T is -CH2-, an oxygen atom, -S(O)i- (i is an integer 0-2), or -NR7-; X is an oxygen atom, a sulfur atom, or -NR7-; the ring (A''') is a benzene ring or a pyridine ring; the ring (B') is a benzene ring, a pyridine ring, or a pyrimidine ring; and R1-R14 represent specific groups), a salt thereof, or a solvate of the compound or salt. |
申请人 |
MOCHIDA PHARMACEUTICAL CO.,LTD.;OKANO, AKIHIRO;OHKOUCHI, MUNETAKA;MAKABE, MUNEYOSHI |
发明人 |
OKANO, AKIHIRO;OHKOUCHI, MUNETAKA;MAKABE, MUNEYOSHI |