发明名称 |
RADIOPAQUE INJECTABLE NUCLEUS HYDROGEL COMPOSITIONS |
摘要 |
In one embodiment, the invention relates to a composition suitable for preparing a hydrogel useful as replacement material for all or part of a disc nucleus. The composition comprises: a curable, cross-linkable, non-immunogenic, non-toxic protein comprising a minimum of about 10% and a maximum of about 25% of the hydrogel by weight; a metal contrast agent comprising a minimum of about 2% and a maximum of about 70% of the hydrogel by weight; and a crosslinker comprising a minimum of about 0.1% and a maximum of about 10% of the hydrogel by weight; wherein the composition has a discernable radiopacity level.
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申请公布号 |
US2012276008(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
US201113094512 |
申请日期 |
2011.04.26 |
申请人 |
WALKENHORST JARED W.;COLLINS KEITH A.;LEE DENNIS Y.;WILSON THOMAS G.;DOUVILLE THOMAS J.;BERLEMANN ULRICH;SPINE WAVE, INC. |
发明人 |
WALKENHORST JARED W.;COLLINS KEITH A.;LEE DENNIS Y.;WILSON THOMAS G.;DOUVILLE THOMAS J.;BERLEMANN ULRICH |
分类号 |
A61K49/00 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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