摘要 |
Described herein are methods for determining a Caucasian subject's susceptibility to having or developing a complement-mediated disease comprising determining in the Caucasian subject the identity of one or more haplotypes, wherein the one or more haplotypes are HI_62_A, H2_62_A, H3_62_A, H4_62_A, H5_62_A, H6_62_A, H7 62_A, H8 62_A, H9_62_A, HI0_62_A, HII_62_A, H12 62_A, H13_62_A, HI4_62_A, HI5_62_A, or a complement thereof, and wherein the presence of one or more of the haplotypes indicates the subject's susceptibility for having or developing a complement-mediated disease. |