发明名称 |
Agents, Uses and Methods |
摘要 |
The present invention relates to therapeutic agents for the targeted delivery of an immunosuppressive agent to monocytes and/or monocyte-derived cells comprising a binding moiety with specificity for monocytes and/or monocyte-derived cells and an immunosuppressive agent. In one embodiment, the agent is a glucocorticoid-antibody conjugate. The invention also relates to methods, uses, kits and compositions comprising such agents. |
申请公布号 |
US2012276193(A1) |
申请公布日期 |
2012.11.01 |
申请号 |
US201013498511 |
申请日期 |
2010.09.29 |
申请人 |
GRAVERSEN NIELS JONAS HEILSKOV;SVENDSEN PIA;CHRISTENSEN PETER ASTRUP;MOESTRUP SOEREN KRAGH;MOELLER HOLGER JON;ANTON GABRIELE |
发明人 |
GRAVERSEN NIELS JONAS HEILSKOV;SVENDSEN PIA;CHRISTENSEN PETER ASTRUP;MOESTRUP SOEREN KRAGH;MOELLER HOLGER JON;ANTON GABRIELE |
分类号 |
A61K39/395;A61K9/127;A61K39/44;A61P29/00;A61P37/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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