发明名称 NOVEL 3-HYDROXYISOTHIAZOLE 1-OXIDE DERIVATIVE
摘要 [Problem] To provide a GPR40 activating agent having as an active ingredient a novel compound having a GPR40 agonist action, a salt thereof, a solvate of the compound or salt, or the like; in particular, an insulin secretagogue or an agent for preventing and/or treating diabetes, obesity, or the like. [Solution] A compound represented by formula (I) [Chemical formula 1] (in the formula, p is 0-4; j is 0-1; k is 0-2; the ring (A) is a heterocyclic group, cycloalkyl group, cycloalkenyl group, spiro ring group, or aryl group optionally substituted at the position (L); the ring (B) is an aryl group or a heteroaryl group; X is O or -NR7-; and R1-R7 and L represent specific groups), a salt thereof, or a solvate of the compound or salt.
申请公布号 CA2834417(A1) 申请公布日期 2012.11.01
申请号 CA20122834417 申请日期 2012.04.11
申请人 MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 OHKOUCHI, MUNETAKA
分类号 C07D275/02;A61K31/4155;A61K31/425;A61K31/427;A61K31/435;A61K31/438;A61K31/4439;A61K31/454;A61K31/501;A61K31/506;A61K31/5377;A61K45/00;A61P3/04;A61P3/10;A61P43/00;C07D417/12;C07D417/14;C07D471/10;C07D491/107;C07D491/20 主分类号 C07D275/02
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