发明名称 IP-10 ANTIBODY DOSAGE ESCALATION REGIMENS
摘要 In certain embodiments, the present invention provides a method of treating an IP10 -related disease in a subject, comprising: (a) administering to the subject a predetermined dosage of an anti-IPIO antibody; (b) detecting the level of the anti-IPIO antibody in a sample of the subject; and (c) if the level of the anti-IPIO antibody from step (b) is below a threshold exposure level, increasing the dosage of the anti-IPIO antibody in the subject such that the IP-10 related disease in the subject is treated.
申请公布号 CA2834552(A1) 申请公布日期 2012.11.01
申请号 CA20122834552 申请日期 2012.04.27
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 LUO, ALLISON Y.;TRIGONA, WENDY L.;SHEN, JINSHAN;XU, LI-AN;ZHANG, YAN;STOUFFER, BRUCE;CHEN, HAIBIN;HUANG, HAICHUN;TAO, XIAOLU;BROCKUS, CATHERINE
分类号 C07K16/24;C07K16/42 主分类号 C07K16/24
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