发明名称 |
PROCESS FOR PREPARING A BENZOYLBENZENEACETAMIDE DERIVATIVE |
摘要 |
Disclosed is a process for preparing anti-inflammatory compound nepafenac comprising preparing a compound of formula (V) wherein a N-halosuccinimide is used as the halogenating agent, followed by desulfurization using Raney Nickel. Also disclosed is a polymorphic form B of 2-amino-3-benzoyl-α-(methylthio)-benzeneacetamide (i.e., a compound of formula (V) wherein R is methyl |
申请公布号 |
HRP20120550(T1) |
申请公布日期 |
2012.10.31 |
申请号 |
HR2012P000550T |
申请日期 |
2012.07.05 |
申请人 |
MEDICHEM, S.A. |
发明人 |
TOJO SUAREZ, GABRIEL;GAVALDA ESCUDE, ANA |
分类号 |
C07C233/33;A61K31/165;A61P7/02;C07C323/60 |
主分类号 |
C07C233/33 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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