| 发明名称 |
Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
| 摘要 |
A four arm-polyethylene glycol-7-ethyl-10-hydroxycamptothecin conjugate, such as, is disclosed. Methods of making the conjugates and methods of treating mammals using the same are also disclosed. |
| 申请公布号 |
US8299089(B2) |
申请公布日期 |
2012.10.30 |
| 申请号 |
US20100762434 |
申请日期 |
2010.04.19 |
| 申请人 |
ZHAO HONG;RUBIO MARIA BELEN;WU DECHUN;SAPRA PUJA;ENZON PHARMACEUTICALS, INC. |
发明人 |
ZHAO HONG;RUBIO MARIA BELEN;WU DECHUN;SAPRA PUJA |
| 分类号 |
A61K31/4745;C07D491/22 |
主分类号 |
A61K31/4745 |
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