发明名称 |
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING FATTY LIVER DISEASE COMPRISING EXTRACT OF CYPERI RHIZOMA |
摘要 |
PURPOSE: A pharmaceutical composition for treating and preventing steatosis which contains cyperi rhizoma extracts is provided to obstruct inter-combination between LSR and TRAP80. CONSTITUTION: A pharmaceutical composition for treating and preventing steatosis contains cyperi rhizoma extracts. The steatosis is alcohol steatosis or vial call steatosis. The cyperi rhizoma suppresses lipogenesis by controlling inter-combination between TRAP80 and LXR. The cyperi rhizoma extract selectively controls transcription of SREBP-1c. The cyperi rhizoma extract is extracted with C1-4 alcohol, hexane, cychlohexan, methylene chloride, chloroform, ether(ethyl ether), ethyl acetate, water or a mixed solvent thereof. The cyperi rhizoma extract is obtained by the following steps: extracting the cyperi rhizoma with methanol or ethanol; suspending the methanol or ethanol extract in distilled water; adding identical amount of hexane as distilled water and partitioning thereof.
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申请公布号 |
KR20120118736(A) |
申请公布日期 |
2012.10.29 |
申请号 |
KR20110036298 |
申请日期 |
2011.04.19 |
申请人 |
UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION;KABIO R&D SOO CO., LTD. |
发明人 |
KIM, SEUNG WHAN;KWAK, JONG HWAN;OH, GYUN SIK |
分类号 |
A61K36/8905;A61P1/00;A61P1/16 |
主分类号 |
A61K36/8905 |
代理机构 |
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