| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine. What is presented is a lyophilised preparation containing at least one nicotine - virus-like particle conjugate, and a stabiliser composition containing at least one nonreducing disaccharide and at least one non-ionic surfactant wherein the pre-lyophilisation pH value of the stabiliser composition makes 5.8 to 6.6, preferentially 6.0 to 6.4. ^ EFFECT: invention provides producing the effective lyophilised vaccinal preparation able to keep stability for a long period of time. ^ 14 cl, 3 dwg, 4 tbl, 6 ex |
