| 发明名称 |
METHOD FOR IMPROVING IMMUNOGENICITY OF COLD-ADAPTED LIVE INFLUENZA VACCINE |
| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medical industry and concerns production of a live influenza xa vaccine. The method for improving immunogenicity of the cold-adapted influenza vaccine is characterised by the fact that the vaccine is added by an adjuvant presented by chitosonium glutamate of final concentration 0.5% having a degree of deacetylation within 66-99% and molecular weight within 70-500 kDa. ^ EFFECT: method is easy to implement and enables effectively improving immunogenicity of the cold-adapted influenza vaccine. ^ 5 tbl, 5 ex |
| 申请公布号 |
RU2465006(C2) |
申请公布日期 |
2012.10.27 |
| 申请号 |
RU20100114819 |
申请日期 |
2010.04.14 |
| 申请人 |
UCHREZHDENIE ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT VAKTSIN I SYVOROTOK IM. I.I. MECHNIKOVA RAMN (NIIVS IM. I.I. MECHNIKOVA RAMN) |
发明人 |
GENDON JURIJ ZAKHAROVICH;MARKUSHIN STANISLAV GEORGIEVICH;AKOPOVA IRINA IVANOVNA;KRIVTSOV GEORGIJ GEORGIEVICH;PEREVERZEV ALEKSANDR DIMITRIEVICH;SUKHNO ANATOLIJ SERGEEVICH |
| 分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
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