| 发明名称 |
3-(2,2,2-TRIMETHYLHYDRAZINIUM) PROPIONATE DERIVATIVE -3-(2,2,2-TRIMETHYLHYDRAZINIUM) POTASSIUM PROPIONATE NICOTINATE DERIVATIVE EXHIBITING ENDOTHELIOPROTECTIVE ACTIVITY |
| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, more specifically to a new chemical compound, a 3-(2,2,2-trimethylhydrazinium)propionate derivative - 3-(2,2,2-trimethylhydrazinium)potassium propionate nicotinate, (CH3)3N+NHCH2CH2COOKRCOO--wherein R= , showing endothelioprotective activity. ^ EFFECT: derivative can find application in medicine in the integrated treatment for endothelial dysfunction correction in cardiovascular diseases. ^ 1 cl, 2 ex, 1 tbl |
| 申请公布号 |
RU2465268(C1) |
申请公布日期 |
2012.10.27 |
| 申请号 |
RU20110133232 |
申请日期 |
2011.08.08 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "BELGORODSKIJ GOSUDARSTVENNYJ NATSIONAL'NYJ ISSLEDOVATEL'SKIJ UNIVERSITET" |
发明人 |
DANILENKO LJUDMILA MIKHAJLOVNA;KHARITONOVA OL'GA VLADIMIROVNA;SERNOV LEV NIKOLAEVICH;SKACHILOVA SOFIJA JAKOVLEVNA;KESAREV OLEG GEORGIEVICH;SERNOVA ALEKSANDRA L'VOVNA;KESAREVA ZINAIDA ALEKSANDROVNA;POKROVSKIJ MIKHAIL VLADIMIROVICH;NOVIKOV OLEG OLEGOVICH;POKROVSKAJA TAT'JANA GRIGOR'EVNA;ZHILJAKOVA ELENA TEODOROVNA;KOCHKAROV VLADIMIR ISKHAKOVICH;NOVIKOVA MARINA JUR'EVNA;KLOCHKOVA GALINA NIKOLAEVNA;DUDINSKIKH ANASTASIJA JUR'EVNA;KOVALENKO BORIS STEPANOVICH;GOLIVETS TAT'JANA PAVLOVNA;PANICHEVA OL'GA MIKHAJLOVNA;BELJAEV KIRILL ALEKSANDROVICH;KHAVANSKIJ ANATOLIJ VJACHESLAVOVICH |
| 分类号 |
C07D213/80 |
主分类号 |
C07D213/80 |
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