pCAGGS VECTOR COMPRISING AN 829 BASE PAIR DELETION IN THE CHICKEN-BETA ACTIN INTRON WHICH RESULTS IN ENHANCED EXPRESSION OF A GENE OF INTEREST

摘要

Disclosed is a pCAGGS vector with an optimized CAG promoter sequence consisting of a nucleotide sequence as set forth in SEQ ID No.1 . Also disclosed is A CAG promoter sequence having a nucleotide sequence as set forth in SEQ ID No. 1 operably linked to a nucleic acid sequence comprising a Kozak sequence and a nucleic acid sequence encoding a codon-optimized Ebola virus glycoprotein as set forth in SEQ ID No. 2.