发明名称 Amino Acid Prodrugs
摘要 Provided is a drug-conjugate product obtained by reacting the drug with an alpha-amino acid selected from Lys, Leu, He, Gly, Asp, Glu, Met, Ala, Val, His, Nor, Arg, Phe, Trp, Hsr, Car, Ort, Cav, Asn, GIn, Can, Tau, Djk, GABA, Cys, Dcy and Sar, under conditions effective to form a compound having a covalent bond between the drug and the amino acid, wherein the drug is selected from a list of specified drugs (including ibuprofen and aspirin).
申请公布号 NZ601780(A) 申请公布日期 2012.10.26
申请号 NZ20040601780 申请日期 2004.07.29
申请人 SIGNATURE R & D HOLDINGS, LLC 发明人 CHANDRAN, V
分类号 A61K38/00;A01N37/18;A01N43/42;A61K;C07K5/06;C07K7/64 主分类号 A61K38/00
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