| 发明名称 |
MODIFIED ACID ALPHA GLUCOSIDASE WITH ACCELERATED PROCESSING |
| 摘要 |
A modified human acid alpha-glucosidase polypeptide having increased hydrophobicity at or near the N- terminal 70 kDa processing site is provided, as well as methods of making and using the modified human acid alpha-glucosidase to treat glycogen storage disorders. |
| 申请公布号 |
CA2833371(A1) |
申请公布日期 |
2012.10.26 |
| 申请号 |
CA20122833371 |
申请日期 |
2012.04.20 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
CANFIELD, WILLIAM M.;MORELAND, RODNEY J.;KUDO, MARIKO |
| 分类号 |
C12N9/24;A61K38/47 |
主分类号 |
C12N9/24 |
| 代理机构 |
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代理人 |
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| 主权项 |
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