发明名称 |
Method for evaluating synthesis of new fibrillar collagen in reconstructed skin in e.g. human, involves acquiring three-dimensional two-photon excitation fluorescence signals and second harmonic generation signal |
摘要 |
The method involves acquiring three-dimensional two-photon excitation fluorescence (2PEF) signals and a second harmonic generation (SHG) signal of fibrillar collagen in a sample of skin (13) by performing multiphoton microscopy. Information indicative of the distribution and/or the amount of fibrillar collagen in the skin is generated based on the acquired three-dimensional 2PEF fluorescence signals and the SHG signal, where the information is generated in a form of image. |
申请公布号 |
FR2974287(A1) |
申请公布日期 |
2012.10.26 |
申请号 |
FR20110053383 |
申请日期 |
2011.04.19 |
申请人 |
L'OREAL |
发明人 |
AZADIGUIAN GAYANE;PENA ANA-MARIA;BLACK ANNIE;COLONNA ANNE |
分类号 |
A61B5/103 |
主分类号 |
A61B5/103 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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