ANALYZING THE EXPRESSION OF BIOMARKERS IN CELLS WITH MOMENTS
摘要
Cell profile data is stored. The cell profile data comprises multiplexed biometric images capturing the expression of a plurality of biomarkers by at least one tissue sample from a patient with respect to at least one field of view. Individual cells are delineated and segmented into compartments. At least one cell feature is calculated based on the cell's expression of each of a plurality of biomarkers. A first moment is calculated for each cell feature. The moments are examined for an association with a diagnosis, a prognosis of a response to treatment of a condition or disease. Apparatus for performing the foregoing steps are disclosed.
申请公布号
WO2012143556(A2)
申请公布日期
2012.10.26
申请号
WO2012EP57387
申请日期
2012.04.23
申请人
GENERAL ELECTRIC COMPANY;GE HEALTHCARE LIMITED;MCCULLOCH, COLIN, CRAIG;GINTY, FIONA;SEVINSKY, CHRISTOPHER, JAMES
发明人
MCCULLOCH, COLIN, CRAIG;GINTY, FIONA;SEVINSKY, CHRISTOPHER, JAMES