Balloon catheter medical device coated with therapeutic agent and povidone-iodine

摘要

Disclosed is a medical disposable device (such as a balloon catheter) for local delivery of a hydrophobic therapeutic agent comprising: an expandable structure having an outer surface; and a non-durable coating disposed on the outer surface of the expandable structure, said non-durable coating comprising a non-covalently bound iodine in a polymer matrix (such as povidone-iodine) which is dissolvable in both aqueous and non-aqueous solution and wherein a hydrophobic therapeutic agent (such as paclitaxel or dexamethasone acetate) is dispersed in the polymer matrix.