MODIFIED VARIABLE DOMAIN MOLECULES AND METHODS FOR PRODUCING AND USING THEM B
摘要
The present disclosure provides an isolated protein comprising an antibody light chain variable domain (VL) comprising at least one negatively charged amino acid positioned between residues 49 to 56 according to the numbering system of Kabat, the protein capable of binding specifically to an antigen.
申请公布号
WO2012142662(A1)
申请公布日期
2012.10.26
申请号
WO2012AU00403
申请日期
2012.04.19
申请人
GARVAN INSTITUTE OF MEDICAL RESEARCH;CHRIST, DANIEL;DUDGEON, KIP;ROUET, ROMAIN