发明名称 |
METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME |
摘要 |
The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
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申请公布号 |
US2012270850(A1) |
申请公布日期 |
2012.10.25 |
申请号 |
US20070515473 |
申请日期 |
2007.11.20 |
申请人 |
BARNHAM KEVIN JEFFREY;DONNELLY PAUL STEPHEN;WHITE ANTHONY ROBERT;UNIVERSITY OF MEDLBOURNE |
发明人 |
BARNHAM KEVIN JEFFREY;DONNELLY PAUL STEPHEN;WHITE ANTHONY ROBERT |
分类号 |
A61K31/555;A61K31/30;A61K31/315;A61P1/00;A61P9/00;A61P9/10;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P27/02;A61P27/06;A61P27/12;A61P33/06;A61P35/00;C12N5/07 |
主分类号 |
A61K31/555 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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