| 发明名称 |
ENHANCEMENT OF REGENERATION BY MODULATION OF NOTUM ACTIVITY |
| 摘要 |
The invention provides compositions and methods of use for identifying modulators of NOTUM, e.g., NOTUM inhibitors. In some aspects, identified compounds are useful for modulating Wnt signaling at sites of tissue damage. The invention further provides methods of promoting regeneration by inhibiting NOTUM.
|
| 申请公布号 |
US2012269798(A1) |
申请公布日期 |
2012.10.25 |
| 申请号 |
US201213427660 |
申请日期 |
2012.03.22 |
| 申请人 |
REDDIEN PETER;PETERSEN CHRISTIAN |
发明人 |
REDDIEN PETER;PETERSEN CHRISTIAN |
| 分类号 |
A61K38/02;A61K31/70;A61K31/7088;A61K39/395;A61P43/00;C12N1/15;C12N5/10;C12Q1/34;G01N21/76 |
主分类号 |
A61K38/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
