发明名称 |
METHOD FOR CONSTRUCTING CHIMERIC RAT USING RAT EMBRYONIC STEM CELLS |
摘要 |
The present invention provides a preparation method of a chimeric embryo and a chimeric rat, which is characterized by contacting a rat pluripotent stem cell and a host embryo in the presence of an ES cell differentiation inhibitor. The method includes (a) a step for contacting a fertilized host embryo collected from a female rat and a rat pluripotent stem cell in the presence of an ES cell differentiation suppressant, and (b) a step for culturing the host embryo in contact with the rat pluripotent stem cell to form a chimeric embryo. |
申请公布号 |
US2012272349(A1) |
申请公布日期 |
2012.10.25 |
申请号 |
US201013513100 |
申请日期 |
2010.11.30 |
申请人 |
OCHIYA TAKAHIRO;KAWAMATA MASAKI;DS PHARMA BIOMEDICAL CO., LTD.;NATIONAL CANCER CENTER |
发明人 |
OCHIYA TAKAHIRO;KAWAMATA MASAKI |
分类号 |
C12N15/85;A01K67/027;C12N5/02 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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