发明名称 COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS
摘要 The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited.
申请公布号 US2012269724(A1) 申请公布日期 2012.10.25
申请号 US201113325051 申请日期 2011.12.13
申请人 MAHMOOD ASHFAQ;JONES ALUN G.;LIMPA-AMARA NAENGNOI;PENG YIJIE;AKGUN ZEYNEP;PRESIDENT AND FELLOWS OF HARVARD COLLEGE 发明人 MAHMOOD ASHFAQ;JONES ALUN G.;LIMPA-AMARA NAENGNOI;PENG YIJIE;AKGUN ZEYNEP
分类号 A61K51/04;C07C215/50;C07C323/60;C07D211/14;C07D211/22;C07D213/36;C07D295/13;C07D333/20;C07D401/12;C07D409/12;C07F13/00;G01N33/60 主分类号 A61K51/04
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