发明名称 |
Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
摘要 |
This invention relates to the field of therapeutics. Most specifically, the invention provides methods of generating conditionally expressing vectors for one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. These vector may be provided to treat a variety of disorders, e.g., neoplastic disorders, through direct injection or through in vitro engineered cells, such as dendritic cells. |
申请公布号 |
AU2011232435(A1) |
申请公布日期 |
2012.10.25 |
申请号 |
AU20110232435 |
申请日期 |
2011.03.23 |
申请人 |
INTREXON CORPORATION |
发明人 |
ROETH, JEREMIAH F.;REED, CHARLES C.;CUTHBERTSON, BRANDON;CHADA, SUNIL;FOGLER, WILLIAM E. |
分类号 |
C12N15/00 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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